Effect of Anticancer Drugs on Histology of Salivary Glands in Some Laboratory Animals

Cancer chemotherapeutic agents are not selective for tumor cells, unfortunately, they damage normal cells. This is based on the type, amount and duration of drug used to treat the cancer. Salivary gland tissues can be affected resulting in morphological and functional changes with an oral manifestation which are especial prominent feature of the toxicity leading mainly to reduction of saliva flow namely xerostomia. The objective was to analyze the effects of anticancer drugs on salivary glands of some animals.